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Systematic error detection in experimental high-throughput screening

BACKGROUND: High-throughput screening (HTS) is a key part of the drug discovery process during which thousands of chemical compounds are screened and their activity levels measured in order to identify potential drug candidates (i.e., hits). Many technical, procedural or environmental factors can ca...

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Detalles Bibliográficos
Autores principales: Dragiev, Plamen, Nadon, Robert, Makarenkov, Vladimir
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034671/
https://www.ncbi.nlm.nih.gov/pubmed/21247425
http://dx.doi.org/10.1186/1471-2105-12-25