Single amino acid change in gp41 region of HIV-1 alters bystander apoptosis and CD4 decline in humanized mice

BACKGROUND: The mechanism by which HIV infection leads to a selective depletion of CD4 cells leading to immunodeficiency remains highly debated. Whether the loss of CD4 cells is a direct consequence of virus infection or bystander apoptosis of uninfected cells is also uncertain. RESULTS: We have add...

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Detalles Bibliográficos
Autores principales: Garg, Himanshu, Joshi, Anjali, Ye, Chunting, Shankar, Premlata, Manjunath, N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034703/
https://www.ncbi.nlm.nih.gov/pubmed/21255440
http://dx.doi.org/10.1186/1743-422X-8-34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034703/
https://www.ncbi.nlm.nih.gov/pubmed/21255440
http://dx.doi.org/10.1186/1743-422X-8-34

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