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Single amino acid change in gp41 region of HIV-1 alters bystander apoptosis and CD4 decline in humanized mice
BACKGROUND: The mechanism by which HIV infection leads to a selective depletion of CD4 cells leading to immunodeficiency remains highly debated. Whether the loss of CD4 cells is a direct consequence of virus infection or bystander apoptosis of uninfected cells is also uncertain. RESULTS: We have add...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034703/ https://www.ncbi.nlm.nih.gov/pubmed/21255440 http://dx.doi.org/10.1186/1743-422X-8-34 |