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Autoreactive marginal zone B cells enter the follicles and interact with CD4(+ )T cells in lupus-prone mice

BACKGOUND: Marginal zone B cells have been implicated in the production of autoantibodies in murine models of lupus. It has been suggested that they contribute to lupus immunopathogenesis through their enhanced effector functions and their repertoire that is biased toward autoreactive specificities....

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Detalles Bibliográficos
Autores principales: Zhou, Zhenhai, Niu, Haitao, Zheng, Ying-Yi, Morel, Laurence
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034709/
https://www.ncbi.nlm.nih.gov/pubmed/21251257
http://dx.doi.org/10.1186/1471-2172-12-7