Antibodies to a Full-Length VAR2CSA Immunogen Are Broadly Strain-Transcendent but Do Not Cross-Inhibit Different Placental-Type Parasite Isolates

The high molecular weight, multidomain VAR2CSA protein mediating adhesion of Plasmodium falciparum-infected erythrocytes in the placenta is the leading candidate for a pregnancy malaria vaccine. However, it has been difficult so far to generate strong and consistent adhesion blocking antibody respon...

Descripción completa

Detalles Bibliográficos
Autores principales: Avril, Marion, Hathaway, Marianne J., Srivastava, Anand, Dechavanne, Sébastien, Hommel, Mirja, Beeson, James G., Smith, Joseph D., Gamain, Benoît
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034725/
https://www.ncbi.nlm.nih.gov/pubmed/21326877
http://dx.doi.org/10.1371/journal.pone.0016622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034725/
https://www.ncbi.nlm.nih.gov/pubmed/21326877
http://dx.doi.org/10.1371/journal.pone.0016622

Ejemplares similares