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Efficient Generation of Hepatoblasts From Human ES Cells and iPS Cells by Transient Overexpression of Homeobox Gene HEX

Human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have the potential to differentiate into all cell lineages, including hepatocytes, in vitro. Induced hepatocytes have a wide range of potential application in biomedical research, drug discovery, and the treatment of liver...

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Detalles Bibliográficos
Autores principales: Inamura, Mitsuru, Kawabata, Kenji, Takayama, Kazuo, Tashiro, Katsuhisa, Sakurai, Fuminori, Katayama, Kazufumi, Toyoda, Masashi, Akutsu, Hidenori, Miyagawa, Yoshitaka, Okita, Hajime, Kiyokawa, Nobutaka, Umezawa, Akihiro, Hayakawa, Takao, Furue, Miho K, Mizuguchi, Hiroyuki
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034848/
https://www.ncbi.nlm.nih.gov/pubmed/21102561
http://dx.doi.org/10.1038/mt.2010.241