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Efficient Generation of Hepatoblasts From Human ES Cells and iPS Cells by Transient Overexpression of Homeobox Gene HEX
Human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have the potential to differentiate into all cell lineages, including hepatocytes, in vitro. Induced hepatocytes have a wide range of potential application in biomedical research, drug discovery, and the treatment of liver...
Autores principales: | Inamura, Mitsuru, Kawabata, Kenji, Takayama, Kazuo, Tashiro, Katsuhisa, Sakurai, Fuminori, Katayama, Kazufumi, Toyoda, Masashi, Akutsu, Hidenori, Miyagawa, Yoshitaka, Okita, Hajime, Kiyokawa, Nobutaka, Umezawa, Akihiro, Hayakawa, Takao, Furue, Miho K, Mizuguchi, Hiroyuki |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034848/ https://www.ncbi.nlm.nih.gov/pubmed/21102561 http://dx.doi.org/10.1038/mt.2010.241 |
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