Archaeosome Adjuvant Overcomes Tolerance to Tumor-Associated Melanoma Antigens Inducing Protective CD8(+) T Cell Responses

Vesicles comprised of the ether glycerolipids of the archaeon Methanobrevibacter smithii (archaeosomes) are potent adjuvants for evoking CD8(+) T cell responses. We therefore explored the ability of archaeosomes to overcome immunologic tolerance to self-antigens. Priming and boosting of mice with ar...

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Detalles Bibliográficos
Autores principales: Krishnan, Lakshmi, Deschatelets, Lise, Stark, Felicity C., Gurnani, Komal, Sprott, G. Dennis
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034908/
https://www.ncbi.nlm.nih.gov/pubmed/21318177
http://dx.doi.org/10.1155/2010/578432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034908/
https://www.ncbi.nlm.nih.gov/pubmed/21318177
http://dx.doi.org/10.1155/2010/578432

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