Aberrantly Glycosylated IgA1 as a Factor in the Pathogenesis of IgA Nephropathy

Predominant or codominant immunoglobulin (Ig) A deposition in the glomerular mesangium characterizes IgA nephropathy (IgAN). Accumulated glomerular IgA is limited to the IgA1 subclass and usually galactose-deficient. This underglycosylated IgA may play an important role in the pathogenesis of IgAN....

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Detalles Bibliográficos
Autores principales: Tanaka, Mototsugu, Seki, George, Someya, Tomonosuke, Nagata, Michio, Fujita, Toshiro
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034910/
https://www.ncbi.nlm.nih.gov/pubmed/21318178
http://dx.doi.org/10.1155/2011/470803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034910/
https://www.ncbi.nlm.nih.gov/pubmed/21318178
http://dx.doi.org/10.1155/2011/470803

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