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Expression of UDP-glucuronosyltransferase 1A4 in human placenta at term

The placenta contains a large variety of metabolizing enzymes, among them UDP-glucuronosyltransferase (UGT). Several UGT2B isozymes have so far been detected in human placenta, but little is known on placental expression of UGT1A isozymes. The antiepileptic drug lamotrigine (LTG) is a UGT1A4-substra...

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Detalles Bibliográficos
Autores principales: Reimers, Arne, Østby, Lene, Stuen, Ina, Sundby, Eirik
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034912/
https://www.ncbi.nlm.nih.gov/pubmed/21302032
http://dx.doi.org/10.1007/s13318-010-0021-x