Spectroscopic Characterization of Intermolecular Interaction of Amyloid β Promoted on GM1 Micelles

Clusters of GM1 gangliosides act as platforms for conformational transition of monomeric, unstructured amyloid β (Aβ) to its toxic β-structured aggregates. We have previously shown that Aβ(1–40) accommodated on the hydrophobic/hydrophilic interface of lyso-GM1 or GM1 micelles assumes α-helical struc...

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Detalles Bibliográficos
Autores principales: Yagi-Utsumi, Maho, Matsuo, Koichi, Yanagisawa, Katsuhiko, Gekko, Kunihiko, Kato, Koichi
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034947/
https://www.ncbi.nlm.nih.gov/pubmed/21318130
http://dx.doi.org/10.4061/2011/925073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034947/
https://www.ncbi.nlm.nih.gov/pubmed/21318130
http://dx.doi.org/10.4061/2011/925073

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