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Leucine-rich repeat kinase 2 and alpha-synuclein: intersecting pathways in the pathogenesis of Parkinson's disease?

Although Parkinson's disease (PD) is generally a sporadic neurological disorder, the discovery of monogenic, hereditable forms of the disease has been crucial in delineating the molecular pathways that lead to this pathology. Genes responsible for familial PD can be ascribed to two categories b...

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Detalles Bibliográficos
Autores principales: Greggio, Elisa, Bisaglia, Marco, Civiero, Laura, Bubacco, Luigi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035023/
https://www.ncbi.nlm.nih.gov/pubmed/21244648
http://dx.doi.org/10.1186/1750-1326-6-6