Cleavage of model substrates by archaeal RNase P: role of protein cofactors in cleavage-site selection

RNase P is a catalytic ribonucleoprotein primarily involved in tRNA biogenesis. Archaeal RNase P comprises a catalytic RNase P RNA (RPR) and at least four protein cofactors (RPPs), which function as two binary complexes (POP5•RPP30 and RPP21• RPP29). Exploiting the ability to assemble a functional P...

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Detalles Bibliográficos
Autores principales: Sinapah, Sylvie, Wu, Shiying, Chen, Yu, Pettersson, B. M. Fredrik, Gopalan, Venkat, Kirsebom, Leif A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035440/
https://www.ncbi.nlm.nih.gov/pubmed/20935047
http://dx.doi.org/10.1093/nar/gkq732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035440/
https://www.ncbi.nlm.nih.gov/pubmed/20935047
http://dx.doi.org/10.1093/nar/gkq732

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