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Cleavage of model substrates by archaeal RNase P: role of protein cofactors in cleavage-site selection
RNase P is a catalytic ribonucleoprotein primarily involved in tRNA biogenesis. Archaeal RNase P comprises a catalytic RNase P RNA (RPR) and at least four protein cofactors (RPPs), which function as two binary complexes (POP5•RPP30 and RPP21• RPP29). Exploiting the ability to assemble a functional P...
Autores principales: | Sinapah, Sylvie, Wu, Shiying, Chen, Yu, Pettersson, B. M. Fredrik, Gopalan, Venkat, Kirsebom, Leif A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035440/ https://www.ncbi.nlm.nih.gov/pubmed/20935047 http://dx.doi.org/10.1093/nar/gkq732 |
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