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Reverse transcriptases can clamp together nucleic acids strands with two complementary bases at their 3′-termini for initiating DNA synthesis

We present evidence that the reverse transcriptase (RT) of human immunodeficiency virus type-1 stabilizes in vitro very short (2-nt) duplexes of 3′-overhangs of the primer strand that are annealed to complementary dinucleotides tails of DNA or RNA template strands, provided that these sequences cont...

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Detalles Bibliográficos
Autores principales: Oz-Gleenberg, Iris, Herschhorn, Alon, Hizi, Amnon
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035444/
https://www.ncbi.nlm.nih.gov/pubmed/20876692
http://dx.doi.org/10.1093/nar/gkq786