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BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cells

Telomerase activity, not detectable in somatic cells but frequently activated during carcinogenesis, confers immortality to tumors. Mechanisms governing expression of the catalytic subunit hTERT, the limiting factor for telomerase activity, still remain unclear. We previously proposed a model in whi...

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Detalles Bibliográficos
Autores principales: Renaud, Stéphanie, Loukinov, Dmitri, Alberti, Loredana, Vostrov, Alexander, Kwon, Yoo-Wook, Bosman, Fred T., Lobanenkov, Victor, Benhattar, Jean
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035453/
https://www.ncbi.nlm.nih.gov/pubmed/20876690
http://dx.doi.org/10.1093/nar/gkq827