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Dual-specificity phosphatase 23 mediates GCM1 dephosphorylation and activation

Glial cells missing homolog 1 (GCM1) is a transcription factor essential for placental development. GCM1 promotes syncytiotrophoblast formation and placental vasculogenesis by activating fusogenic and proangiogenic gene expression in placenta. GCM1 activity is regulated by multiple post-translationa...

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Detalles Bibliográficos
Autores principales: Lin, Fang-Yu, Chang, Ching-Wen, Cheong, Mei-Leng, Chen, Hsei-Chorn, Lee, Der-Yen, Chang, Geen-Dong, Chen, Hungwen
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035457/
https://www.ncbi.nlm.nih.gov/pubmed/20855292
http://dx.doi.org/10.1093/nar/gkq838