Cargando…
Centromere-associated topoisomerase activity in bloodstream form Trypanosoma brucei
Topoisomerase-II accumulates at centromeres during prometaphase, where it resolves the DNA catenations that represent the last link between sister chromatids. Previously, using approaches including etoposide-mediated topoisomerase-II cleavage, we mapped centromeric domains in trypanosomes, early bra...
Autores principales: | , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035458/ https://www.ncbi.nlm.nih.gov/pubmed/20864447 http://dx.doi.org/10.1093/nar/gkq839 |