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Regulation of somatic cell reprogramming through inducible mir-302 expression

Global demethylation is required for early zygote development to establish stem cell pluripotency, yet our findings reiterate this epigenetic reprogramming event in somatic cells through ectopic introduction of mir-302 function. Here, we report that induced mir-302 expression beyond 1.3-fold of the...

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Detalles Bibliográficos
Autores principales: Lin, Shi-Lung, Chang, Donald C., Lin, Chun-Hung, Ying, Shao-Yao, Leu, Davey, Wu, David T. S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035461/
https://www.ncbi.nlm.nih.gov/pubmed/20870751
http://dx.doi.org/10.1093/nar/gkq850