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DNA methyltransferase 3b preferentially associates with condensed chromatin

In mammals, DNA methylation is catalyzed by DNA methyltransferases (DNMTs) encoded by Dnmt1, Dnmt3a and Dnmt3b. Since, the mechanisms of regulation of Dnmts are still largely unknown, the physical interaction between Dnmt3b and chromatin was investigated in vivo and in vitro. In embryonic stem cell...

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Detalles Bibliográficos
Autores principales: Kashiwagi, Katsunobu, Nimura, Keisuke, Ura, Kiyoe, Kaneda, Yasufumi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035464/
https://www.ncbi.nlm.nih.gov/pubmed/20923784
http://dx.doi.org/10.1093/nar/gkq870