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The activity of the HIV-1 IRES is stimulated by oxidative stress and controlled by a negative regulatory element
Initiation of translation of the full-length messenger RNA of HIV-1, which generates the viral structural proteins and enzymes, is cap-dependent but can also use an internal ribosome entry site (IRES) located in the 5′ untranslated region. Our aim was to define, through a mutational analysis, region...
Autores principales: | Gendron, Karine, Ferbeyre, Gerardo, Heveker, Nikolaus, Brakier-Gingras, Léa |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035469/ https://www.ncbi.nlm.nih.gov/pubmed/20935056 http://dx.doi.org/10.1093/nar/gkq885 |
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