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End-processing during non-homologous end-joining: a role for exonuclease 1

Non-homologous end-joining (NHEJ) is a critical error-prone pathway of double strand break repair. We recently showed that tyrosyl DNA phosphodiesterase 1 (Tdp1) regulates the accuracy of NHEJ repair junction formation in yeast. We assessed the role of other enzymes in the accuracy of junction forma...

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Detalles Bibliográficos
Autores principales: Bahmed, Karim, Seth, Aman, Nitiss, Karin C., Nitiss, John L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035470/
https://www.ncbi.nlm.nih.gov/pubmed/20935051
http://dx.doi.org/10.1093/nar/gkq886