Cargando…
End-processing during non-homologous end-joining: a role for exonuclease 1
Non-homologous end-joining (NHEJ) is a critical error-prone pathway of double strand break repair. We recently showed that tyrosyl DNA phosphodiesterase 1 (Tdp1) regulates the accuracy of NHEJ repair junction formation in yeast. We assessed the role of other enzymes in the accuracy of junction forma...
Autores principales: | Bahmed, Karim, Seth, Aman, Nitiss, Karin C., Nitiss, John L. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035470/ https://www.ncbi.nlm.nih.gov/pubmed/20935051 http://dx.doi.org/10.1093/nar/gkq886 |
Ejemplares similares
-
Lif1 SUMOylation and its role in non-homologous end-joining
por: Vigasova, Dana, et al.
Publicado: (2013) -
A role for human homologous recombination factors in suppressing microhomology-mediated end joining
por: Ahrabi, Sara, et al.
Publicado: (2016) -
Cdx2 homeoprotein inhibits non-homologous end joining in colon cancer but not in leukemia cells
por: Renouf, Benjamin, et al.
Publicado: (2012) -
Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination
por: Muñoz-Galván, Sandra, et al.
Publicado: (2013) -
Impact of non-homologous end-joining deficiency on random and targeted DNA integration: implications for gene targeting
por: Iiizumi, Susumu, et al.
Publicado: (2008)