Fluoroquinolone Resistance Linked to GyrA, GyrB, and ParC Mutations in Salmonella enterica Typhimurium Isolates in Humans

We report two cases of infection with clonally unrelated, high-level ciprofloxacin-resistant, β-lactamase–producing strains of Salmonella enterica Typhimurium. Resistance was caused by four topoisomerase mutations, in GyrA, GyrB, and ParC and increased drug efflux. Ciprofloxacin treatment failed in...

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Detalles Bibliográficos
Autores principales: Casin, Isabelle, Breuil, Jacques, Darchis, Jean Pierre, Guelpa, Claire, Collatz, Ekkehard
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2003
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035553/
https://www.ncbi.nlm.nih.gov/pubmed/14718091
http://dx.doi.org/10.3201/eid0911.030317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035553/
https://www.ncbi.nlm.nih.gov/pubmed/14718091
http://dx.doi.org/10.3201/eid0911.030317

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