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Molecular mechanism of the schedule-dependent synergistic interaction in EGFR-mutant non-small cell lung cancer cell lines treated with paclitaxel and gefitinib

BACKGROUND: Chemotherapy combined concurrently with TKIs produced a negative interaction and failed to improve survival when compared with chemotherapy or TKIs alone in the treatment of non-small cell lung cancer (NSCLC). The present study investigated the sequence-dependent interaction between pacl...

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Detalles Bibliográficos
Autores principales: Cheng, Hua, An, She-Juan, Dong, Song, Zhang, Yi-Fang, Zhang, Xu-Chao, Chen, Zhi-Hong, Jian-Su, Wu, Yi-Long
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035578/
https://www.ncbi.nlm.nih.gov/pubmed/21255411
http://dx.doi.org/10.1186/1756-8722-4-5