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Skp2 and Skp2B team up against Rb and p53
The Skp2 locus encodes two proteins, Skp2 and Skp2B. The role of Skp2 in the ubiquitin-dependent degradation of key regulators of the retinoblastoma protein pathway has been well established. More recent work from the McCormick's group suggested that Skp2 has an ubiquitin-independent function i...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035582/ https://www.ncbi.nlm.nih.gov/pubmed/21255415 http://dx.doi.org/10.1186/1747-1028-6-1 |