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Nucleosome resection at a double-strand break during Non-Homologous Ends Joining in mammalian cells - implications from repressive chromatin organization and the role of ARTEMIS

BACKGROUND: The S. cerevisiae mating type switch model of double-strand break (DSB) repair, utilizing the HO endonuclease, is one of the best studied systems for both Homologous Recombination Repair (HRR) and direct ends-joining repair (Non-Homologous Ends Joining - NHEJ). We have recently transpose...

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Detalles Bibliográficos
Autores principales: Kanikarla-Marie, Preeti, Ronald, Sharon, De Benedetti, Arrigo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035584/
https://www.ncbi.nlm.nih.gov/pubmed/21255428
http://dx.doi.org/10.1186/1756-0500-4-13