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Noncanonical Compensation of Zygotic X Transcription in Early Drosophila melanogaster Development Revealed through Single-Embryo RNA-Seq

When Drosophila melanogaster embryos initiate zygotic transcription around mitotic cycle 10, the dose-sensitive expression of specialized genes on the X chromosome triggers a sex-determination cascade that, among other things, compensates for differences in sex chromosome dose by hypertranscribing t...

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Detalles Bibliográficos
Autores principales: Lott, Susan E., Villalta, Jacqueline E., Schroth, Gary P., Luo, Shujun, Tonkin, Leath A., Eisen, Michael B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035605/
https://www.ncbi.nlm.nih.gov/pubmed/21346796
http://dx.doi.org/10.1371/journal.pbio.1000590