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Noncanonical Compensation of Zygotic X Transcription in Early Drosophila melanogaster Development Revealed through Single-Embryo RNA-Seq
When Drosophila melanogaster embryos initiate zygotic transcription around mitotic cycle 10, the dose-sensitive expression of specialized genes on the X chromosome triggers a sex-determination cascade that, among other things, compensates for differences in sex chromosome dose by hypertranscribing t...
Autores principales: | Lott, Susan E., Villalta, Jacqueline E., Schroth, Gary P., Luo, Shujun, Tonkin, Leath A., Eisen, Michael B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035605/ https://www.ncbi.nlm.nih.gov/pubmed/21346796 http://dx.doi.org/10.1371/journal.pbio.1000590 |
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