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Reactive Oxygen Species Production and Mitochondrial Dysfunction Contribute to Quercetin Induced Death in Leishmania amazonensis

BACKGROUND: Leishmaniasis, a parasitic disease caused by protozoa of the genus Leishmania, affects more than 12 million people worldwide. Quercetin has generated considerable interest as a pharmaceutical compound with a wide range of therapeutic activities. One such activity is exhibited against the...

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Detalles Bibliográficos
Autores principales: Fonseca-Silva, Fernanda, Inacio, Job D. F., Canto-Cavalheiro, Marilene M., Almeida-Amaral, Elmo Eduardo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035610/
https://www.ncbi.nlm.nih.gov/pubmed/21346801
http://dx.doi.org/10.1371/journal.pone.0014666