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Role of Cell-to-Cell Variability in Activating a Positive Feedback Antiviral Response in Human Dendritic Cells

In the first few hours following Newcastle disease viral infection of human monocyte-derived dendritic cells, the induction of IFNB1 is extremely low and the secreted type I interferon response is below the limits of ELISA assay. However, many interferon-induced genes are activated at this time, for...

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Detalles Bibliográficos
Autores principales: Hu, Jianzhong, Nudelman, German, Shimoni, Yishai, Kumar, Madhu, Ding, Yaomei, López, Carolina, Hayot, Fernand, Wetmur, James G., Sealfon, Stuart C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035661/
https://www.ncbi.nlm.nih.gov/pubmed/21347441
http://dx.doi.org/10.1371/journal.pone.0016614