Inhibition of NF-κB activation sensitizes U937 cells to 3′-azido-3′-deoxythymidine induced apoptosis

In this study, we investigated molecular mechanisms underlying low susceptibility to apoptosis induced by the nucleoside analog azidothymidine (AZT) and the role of nuclear factor-κB (NF-κB) activation in these phenomena. A preliminary screening in different cell lines indicated U937 monocytic cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Matteucci, C, Minutolo, A, Balestrieri, E, Marino-Merlo, F, Bramanti, P, Garaci, E, Macchi, B, Mastino, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035897/
https://www.ncbi.nlm.nih.gov/pubmed/21368854
http://dx.doi.org/10.1038/cddis.2010.58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035897/
https://www.ncbi.nlm.nih.gov/pubmed/21368854
http://dx.doi.org/10.1038/cddis.2010.58

Ejemplares similares