Alterations of brain and cerebellar proteomes linked to Aβ and tau pathology in a female triple-transgenic murine model of Alzheimer's disease

The triple-transgenic Alzheimer (3 × Tg-AD) mouse expresses mutant PS1(M146V), APP(swe), and tau(P301L) transgenes and progressively develops plaques and neurofibrillary tangles with a temporal- and region-specific profile that resembles the neuropathological progression of Alzheimer's disease...

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Detalles Bibliográficos
Autores principales: Ciavardelli, D, Silvestri, E, Viscovo, A Del, Bomba, M, Gregorio, D De, Moreno, M, Ilio, C Di, Goglia, F, Canzoniero, L M T, Sensi, S L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035905/
https://www.ncbi.nlm.nih.gov/pubmed/21368863
http://dx.doi.org/10.1038/cddis.2010.68

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035905/
https://www.ncbi.nlm.nih.gov/pubmed/21368863
http://dx.doi.org/10.1038/cddis.2010.68

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