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Prediction of binding hot spot residues by using structural and evolutionary parameters

In this work, we present a method for predicting hot spot residues by using a set of structural and evolutionary parameters. Unlike previous studies, we use a set of parameters which do not depend on the structure of the protein in complex, so that the predictor can also be used when the interface r...

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Detalles Bibliográficos
Autores principales: Higa, Roberto Hiroshi, Tozzi, Clésio Luis
Formato: Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036045/
https://www.ncbi.nlm.nih.gov/pubmed/21637529
http://dx.doi.org/10.1590/S1415-47572009000300029