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A straightforward multiallelic significance test for the Hardy-Weinberg equilibrium law

Much forensic inference based upon DNA evidence is made assuming Hardy-Weinberg Equilibrium (HWE) for the genetic loci being used. Several statistical tests to detect and measure deviation from HWE have been devised, and their limitations become more obvious when testing for deviation within multial...

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Detalles Bibliográficos
Autores principales: Lauretto, Marcelo S., Nakano, Fabio, Faria, Silvio R., Pereira, Carlos A. B., Stern, Julio M.
Formato: Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036052/
https://www.ncbi.nlm.nih.gov/pubmed/21637528
http://dx.doi.org/10.1590/S1415-47572009000300028