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CTLA4CT60 gene polymorphism is not associated with differential susceptibility to pemphigus foliaceus
Pemphigus foliaceus is an organ-specific autoimmune disease characterized by autoantibodies against the extracellular region of desmoglein 1, a protein that mediates intercellular adhesion in desmosomes. Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a key negative regulator of the T cell i...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Sociedade Brasileira de Genética
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036102/ https://www.ncbi.nlm.nih.gov/pubmed/21637411 http://dx.doi.org/10.1590/S1415-47572010005000073 |