Histone deacetylase inhibitors sodium butyrate and valproic acid delay spontaneous cell death in purified rat retinal ganglion cells

PURPOSE: Histone deacetylase inhibitors (HDACi) have neuroprotective effects under various neurodegenerative conditions, e.g., after optic nerve crush (ONC). HDACi-mediated protection of central neurons by increased histone acetylation has not previously been demonstrated in rat retinal ganglion cel...

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Detalles Bibliográficos
Autores principales: Biermann, Julia, Boyle, Jennifer, Pielen, Amelie, Lagrèze, Wolf Alexander
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036563/
https://www.ncbi.nlm.nih.gov/pubmed/21311741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036563/
https://www.ncbi.nlm.nih.gov/pubmed/21311741

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