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N-Glycans from Porcine Trachea and Lung: Predominant NeuAcα2-6Gal Could Be a Selective Pressure for Influenza Variants in Favor of Human-Type Receptor

It is known that pigs acted as “mixing vessels” for genesis of a new reassortant influenza strain responsible for pandemic H1N1 2009. However, the host factors driving the evolution of a reassorted virus in pigs to ‘jump species’ resulting in a human outbreak remain unclear. N-glycans derived from t...

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Detalles Bibliográficos
Autores principales: Sriwilaijaroen, Nongluk, Kondo, Sachiko, Yagi, Hirokazu, Takemae, Nobuhiro, Saito, Takehiko, Hiramatsu, Hiroaki, Kato, Koichi, Suzuki, Yasuo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036579/
https://www.ncbi.nlm.nih.gov/pubmed/21347401
http://dx.doi.org/10.1371/journal.pone.0016302