Lack of cathepsin activities alter or prevent the development of lung granulomas in a mouse model of sarcoidosis

BACKGROUND: Remodeling of lung tissues during the process of granuloma formation requires significant restructuring of the extra-cellular matrix and cathepsins K, L and S are among the strongest extra-cellular matrix degrading enzymes. Cathepsin K is highly expressed in various pathological granulom...

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Detalles Bibliográficos
Autores principales: Samokhin, Andriy O, Gauthier, Jacques Yves, Percival, M David, Brömme, Dieter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036631/
https://www.ncbi.nlm.nih.gov/pubmed/21251246
http://dx.doi.org/10.1186/1465-9921-12-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036631/
https://www.ncbi.nlm.nih.gov/pubmed/21251246
http://dx.doi.org/10.1186/1465-9921-12-13

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