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Rac1 Targeting Suppresses Human Non-Small Cell Lung Adenocarcinoma Cancer Stem Cell Activity

The cancer stem cell (CSC) theory predicts that a small fraction of cancer cells possess unique self-renewal activity and mediate tumor initiation and propagation. However, the molecular mechanisms involved in CSC regulation remains unclear, impinging on effective targeting of CSCs in cancer therapy...

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Detalles Bibliográficos
Autores principales: Akunuru, Shailaja, Palumbo, Joseph, Zhai, Qihui James, Zheng, Yi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036726/
https://www.ncbi.nlm.nih.gov/pubmed/21347385
http://dx.doi.org/10.1371/journal.pone.0016951