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Integrin-Linked Kinase Overexpression and Its Oncogenic Role in Promoting Tumorigenicity of Hepatocellular Carcinoma

BACKGROUND: Integrin-linked kinase (ILK) was first discovered as an integrin β1-subunit binding protein. It localizes at the focal adhesions and is involved in cytoskeleton remodeling. ILK overexpression and its dysregulated signaling cascades have been reported in many human cancers. Aberrant expre...

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Detalles Bibliográficos
Autores principales: Chan, Jenny, Ko, Frankie Chi Fat, Yeung, Yin-Shan, Ng, Irene Oi-Lin, Yam, Judy Wai Ping
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036736/
https://www.ncbi.nlm.nih.gov/pubmed/21347395
http://dx.doi.org/10.1371/journal.pone.0016984