Interleukin-10 repletion suppresses pro-inflammatory cytokines and decreases liver pathology without altering viral replication in murine cytomegalovirus (MCMV)-infected IL-10 knockout mice

OBJECTIVE AND DESIGN: To determine the role of interleukin-10 (IL-10) in protecting against the deleterious pro-inflammatory cytokine response to murine cytomegalovirus (MCMV), we studied the impact of IL-10 repletion in MCMV-infected IL-10 knockout (KO) mice. MATERIALS AND METHODS: IL-10 KO mice we...

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Detalles Bibliográficos
Autores principales: Tang-Feldman, Yajarayma J., Lochhead, G. Raymond, Lochhead, Stephanie R., Yu, Cindy, Pomeroy, Claire
Formato: Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2010
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036806/
https://www.ncbi.nlm.nih.gov/pubmed/20922456
http://dx.doi.org/10.1007/s00011-010-0259-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036806/
https://www.ncbi.nlm.nih.gov/pubmed/20922456
http://dx.doi.org/10.1007/s00011-010-0259-4

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