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Ruthenium polypyridyl complexes and their modes of interaction with DNA: Is there a correlation between these interactions and the antitumor activity of the compounds?

Various interaction modes between a group of six ruthenium polypyridyl complexes and DNA have been studied using a number of spectroscopic techniques. Five mononuclear species were selected with formula [Ru(tpy)L(1)L(2)]((2−n)+), and one closely related dinuclear cation of formula [{Ru(apy)(tpy)}(2)...

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Detalles Bibliográficos
Autores principales: Corral, Eva, Hotze, Anna C. G., den Dulk, Hans, Leczkowska, Anna, Rodger, Alison, Hannon, Michael J., Reedijk, Jan
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036821/
https://www.ncbi.nlm.nih.gov/pubmed/19085018
http://dx.doi.org/10.1007/s00775-008-0460-x