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Investigation of 15 of the top candidate genes for late-onset Alzheimer’s disease

The 12 genome-wide association studies (GWAS) published to-date for late-onset Alzheimer’s disease (LOAD) have identified over 40 candidate LOAD risk modifiers, in addition to apolipoprotein (APOE) ε4. A few of these novel LOAD candidate genes, namely BIN1, CLU, CR1, EXOC3L2 and PICALM, have shown c...

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Detalles Bibliográficos
Autores principales: Belbin, Olivia, Carrasquillo, Minerva M., Crump, Michael, Culley, Oliver J., Hunter, Talisha A., Ma, Li, Bisceglio, Gina, Zou, Fanggeng, Allen, Mariet, Dickson, Dennis W., Graff-Radford, Neill R., Petersen, Ronald C., Morgan, Kevin, Younkin, Steven G.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036835/
https://www.ncbi.nlm.nih.gov/pubmed/21132329
http://dx.doi.org/10.1007/s00439-010-0924-2