Non-homologous DNA end joining in normal and cancer cells and its dependence on break structures

DNA double-strand breaks (DSBs) are a serious threat to the cell, for if not or miss-repaired, they can lead to chromosomal aberration, mutation and cancer. DSBs in human cells are repaired via non-homologous DNA end joining (NHEJ) and homologous recombination repair pathways. In the former process,...

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Detalles Bibliográficos
Autores principales: Poplawski, Tomasz, Pastwa, Elzbieta, Blasiak, Janusz
Formato: Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2010
Materias:
Mutagenesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036873/
https://www.ncbi.nlm.nih.gov/pubmed/21637496
http://dx.doi.org/10.1590/S1415-47572010005000018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036873/
https://www.ncbi.nlm.nih.gov/pubmed/21637496
http://dx.doi.org/10.1590/S1415-47572010005000018

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