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Non-homologous DNA end joining in normal and cancer cells and its dependence on break structures
DNA double-strand breaks (DSBs) are a serious threat to the cell, for if not or miss-repaired, they can lead to chromosomal aberration, mutation and cancer. DSBs in human cells are repaired via non-homologous DNA end joining (NHEJ) and homologous recombination repair pathways. In the former process,...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Sociedade Brasileira de Genética
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036873/ https://www.ncbi.nlm.nih.gov/pubmed/21637496 http://dx.doi.org/10.1590/S1415-47572010005000018 |