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Modulatory effects of Tabebuia impetiginosa (Lamiales, Bignoniaceae) on doxorubicin-induced somatic mutation and recombination in Drosophila melanogaster

The wing Somatic Mutation and Recombination Test (SMART) in D. melanogaster was used to study genotoxicity of the medicinal plant Tabebuia impetiginosa. Lapachol (naphthoquinone) and β-lapachone (quinone) are the two main chemical constituents of T. impetiginosa. These compounds have several biologi...

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Detalles Bibliográficos
Autores principales: de Sousa, Neila C., de Rezende, Alexandre A. A., da Silva, Regildo M. G., Guterres, Zaira R., Graf, Ulrich, Kerr, Warwick E., Spanó, Mário A.
Formato: Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036921/
https://www.ncbi.nlm.nih.gov/pubmed/21637695
http://dx.doi.org/10.1590/S1415-47572009005000042