[(123)I]-Celecoxib Analogues as SPECT Tracers of Cyclooxygenase-2 in Inflammation

[Image: see text] We report the synthesis and evaluation of a series of iodinated celecoxib analogues as cyclooxygenase-2 (COX-2)-targeted single photon emission computerized tomography (SPECT) imaging agents for the detection of inflammation. The structure−activity relationship identified 5-(4-iodo...

Descripción completa

Detalles Bibliográficos
Autores principales: Uddin, Md. Jashim, Crews, Brenda C., Ghebreselasie, Kebreab, Tantawy, Mohammed N., Marnett, Lawrence J.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037034/
https://www.ncbi.nlm.nih.gov/pubmed/21318094
http://dx.doi.org/10.1021/ml100232q

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037034/
https://www.ncbi.nlm.nih.gov/pubmed/21318094
http://dx.doi.org/10.1021/ml100232q

Ejemplares similares