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[(123)I]-Celecoxib Analogues as SPECT Tracers of Cyclooxygenase-2 in Inflammation

[Image: see text] We report the synthesis and evaluation of a series of iodinated celecoxib analogues as cyclooxygenase-2 (COX-2)-targeted single photon emission computerized tomography (SPECT) imaging agents for the detection of inflammation. The structure−activity relationship identified 5-(4-iodo...

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Detalles Bibliográficos
Autores principales:	Uddin, Md. Jashim, Crews, Brenda C., Ghebreselasie, Kebreab, Tantawy, Mohammed N., Marnett, Lawrence J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Chemical Society 2010
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037034/ https://www.ncbi.nlm.nih.gov/pubmed/21318094 http://dx.doi.org/10.1021/ml100232q

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