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Discovery pipeline for epigenetically deregulated miRNAs in cancer: integration of primary miRNA transcription

BACKGROUND: Cancer is commonly associated with widespread disruption of DNA methylation, chromatin modification and miRNA expression. In this study, we established a robust discovery pipeline to identify epigenetically deregulated miRNAs in cancer. RESULTS: Using an integrative approach that combine...

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Detalles Bibliográficos
Autores principales: Hulf, Toby, Sibbritt, Tennille, Wiklund, Erik D, Bert, Saul, Strbenac, Dario, Statham, Aaron L, Robinson, Mark D, Clark, Susan J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037319/
https://www.ncbi.nlm.nih.gov/pubmed/21255435
http://dx.doi.org/10.1186/1471-2164-12-54